Effect of Fusidic Acid and Some Nitrogen-Containing Derivatives on Liposomal and Mitochondrial Membranes

Effect of Fusidic Acid and Some Nitrogen-Containing Derivatives on Liposomal and Mitochondrial Membranes

The paper assesses the membranotropic action of the natural antibiotic fusidic acid (FA) and its derivatives. It was found that a FA analogue with ethylenediamine moiety (derivative 2), in contrast to native FA and 3,11-dioxime analogue (derivative 1), is able to increase the mobility of the lipid b...

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Bibliographic Details
Main Authors: Mikhail V. Dubinin, Anna I. Ilzorkina, Elena V. Salimova, Manish S. Landage, Ekaterina I. Khoroshavina, Sergey V. Gudkov, Konstantin N. Belosludtsev, Lyudmila V. Parfenova
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Membranes
Subjects:
fusidic acid
liposomes
laurdan
membrane permeability
mitochondria
oxidative phosphorylation
Online Access:https://www.mdpi.com/2077-0375/13/10/835

Internet

https://www.mdpi.com/2077-0375/13/10/835

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