Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance.
Lentiviruses are able to establish persistent infection in their respective hosts despite a potent type-I interferon (IFN-I) response following transmission. A number of IFN-I-induced host factors that are able to inhibit lentiviral replication in vitro have been identified, and these studies sugges...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-07-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4939950?pdf=render |