Berberine enhances the function of db/db mice islet β cell through GLP-1/GLP-1R/PKA signaling pathway in intestinal L cell and islet α cell

Berberine enhances the function of db/db mice islet β cell through GLP-1/GLP-1R/PKA signaling pathway in intestinal L cell and islet α cell

Background: The evidence on berberine stimulating the secretion of GLP-1 in intestinal L cell has been studied. However, few research has explored its role on generating GLP-1 of islet α cell. Our experiment aims to clarify the mechanism of berberine promoting the secretion of GLP-1 in intestinal L...

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Bibliographic Details
Main Authors: Wenbin Wu, Qingsong Xia, Yujin Guo, Hongzhan Wang, Hui Dong, Fuer Lu, Fen Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Pharmacology
Subjects:
berberine
GLP-1
GLP-1r
islet β cell
T2DM
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1228722/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1228722/full

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