Downregulation of the Tumor Suppressor TFF1 Is Required during Induction of Colon Cancer Progression by L1

The immunoglobulin family cell adhesion receptor L1 is induced in CRC cells at the invasive front of the tumor tissue, and confers enhanced proliferation, motility, tumorigenesis, and liver metastasis. To identify putative tumor suppressors whose expression is downregulated in L1-expressing CRC cell...

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Bibliographic Details
Main Authors: Arka Saha, Nancy Gavert, Thomas Brabletz, Avri Ben-Ze’ev
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/18/4478