The DNA repair protein SHPRH is a nucleosome-stimulated ATPase and a nucleosome-E3 ubiquitin ligase

The DNA repair protein SHPRH is a nucleosome-stimulated ATPase and a nucleosome-E3 ubiquitin ligase

Abstract Background Maintenance of genome integrity during DNA replication is crucial to the perpetuation of all organisms. In eukaryotes, the bypass of DNA lesions by the replication machinery prevents prolonged stalling of the replication fork, which could otherwise lead to greater damages such as...

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Bibliographic Details
Main Authors: Joanna Brühl, Jonathan Trautwein, Agnes Schäfer, Uwe Linne, Karim Bouazoune
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Epigenetics & Chromatin
Subjects:
SHPRH
DNA repair
SNF2
Nucleosome
Ubiquitination/ubiquitylation
Online Access:http://link.springer.com/article/10.1186/s13072-019-0294-5

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http://link.springer.com/article/10.1186/s13072-019-0294-5

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