Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration

Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration

Photoreceptor loss is the principal cause of blindness in retinal degenerative diseases (RDDs). Whereas some therapies exist for early stages of RDDs, no effective treatment is currently available for later stages, and once photoreceptors are lost, the only option to rescue vision is cell transplant...

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Bibliographic Details
Main Authors: Anna Salas, Anna Duarri, Laura Fontrodona, Diana Mora Ramírez, Anna Badia, Helena Isla-Magrané, Barbara Ferreira-de-Souza, Miguel Ángel Zapata, Ángel Raya, Anna Veiga, José García-Arumí
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
cell therapy
human-induced pluripotent stem cell
retinal pigment epithelium
photoreceptors
retina degeneration
RCS rat
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000218

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http://www.sciencedirect.com/science/article/pii/S2329050121000218

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