Current status and applications of genome-scale metabolic models

Abstract Genome-scale metabolic models (GEMs) computationally describe gene-protein-reaction associations for entire metabolic genes in an organism, and can be simulated to predict metabolic fluxes for various systems-level metabolic studies. Since the first GEM for Haemophilus influenzae was report...

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Bibliographic Details
Main Authors: Changdai Gu, Gi Bae Kim, Won Jun Kim, Hyun Uk Kim, Sang Yup Lee
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-019-1730-3