Drug Repurposing to Circumvent Immune Checkpoint Inhibitor Resistance in Cancer Immunotherapy

Drug Repurposing to Circumvent Immune Checkpoint Inhibitor Resistance in Cancer Immunotherapy

Immune checkpoint inhibitors (ICI) have achieved unprecedented clinical success in cancer treatment. However, drug resistance to ICI therapy is a major hurdle that prevents cancer patients from responding to the treatment or having durable disease control. Drug repurposing refers to the application...

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Bibliographic Details
Main Authors: Kenneth K. W. To, William C. Cho
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
PD-1
PD-L1
drug repurposing
tumor microenvironment
drug resistance
immune checkpoint inhibitors
Online Access:https://www.mdpi.com/1999-4923/15/8/2166

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https://www.mdpi.com/1999-4923/15/8/2166

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