Heterochromatin assembly by interrupted Sir3 bridges across neighboring nucleosomes

Heterochromatin is a conserved feature of eukaryotic chromosomes with central roles in regulation of gene expression and maintenance of genome stability. Heterochromatin formation involves spreading of chromatin-modifying factors away from initiation points over large DNA domains by poorly understoo...

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Bibliographic Details
Main Authors: Reza Behrouzi, Chenning Lu, Mark A Currie, Gloria Jih, Nahid Iglesias, Danesh Moazed
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/17556