Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates

Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates

Medulloblastoma is a common pediatric brain tumor and one of the main types of solid cancers in children below the age of 10. Recently, cholesterol-lowering “statin” drugs have been highlighted for their possible anti-cancer effects. Clinically, statins are reported to have promising potential for c...

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Bibliographic Details
Main Authors: Kimia Sheikholeslami, Annan Ali Sher, Sandhini Lockman, Daniel Kroft, Meysam Ganjibakhsh, Kazem Nejati-Koshki, Shahla Shojaei, Saeid Ghavami, Mojgan Rastegar
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
medulloblastoma
brain tumor
apoptosis
mevalonate cascade inhibition
simvastatin
Online Access:https://www.mdpi.com/2072-6694/11/7/994

Internet

https://www.mdpi.com/2072-6694/11/7/994

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