THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation

<p>Abstract</p> <p>Background</p> <p>PGF2alpha exerts a significant contractile effect on myometrium and is central to human labour. THG113.31, a specific non-competitive PGF2alpha receptor (FP) antagonist, exerts an inhibitory effect on myometrial contractility. The BK...

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Bibliographic Details
Main Authors: Morrison John J, Sexton Donal J, O'Reilly Michael J, Doheny Helen C
Format: Article
Language:English
Published: BMC 2007-03-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/5/1/10