The Central Nervous System Contains ILC1s That Differ From NK Cells in the Response to Inflammation

The Central Nervous System Contains ILC1s That Differ From NK Cells in the Response to Inflammation

Innate lymphoid cells (ILCs) are tissue resident cells with organ-specific properties. Here, we show that the central nervous system (CNS) encompasses ILCs. In particular, CD3−NK1.1+ cells present in the murine CNS comprise natural killer (NK) cells, ILC1s, intermediate ILC1s (intILC1s) and ex-ILC3s...

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Bibliographic Details
Main Authors: Silvina Romero-Suárez, Alba Del Rio Serrato, Roemel Jeusep Bueno, Daniel Brunotte-Strecker, Christina Stehle, Caio Andreeta Figueiredo, Laura Hertwig, Ildiko R. Dunay, Chiara Romagnani, Carmen Infante-Duarte
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
innate lymphoid cells (ILCs)
ILC1s
natural killer (NK) cells
central nervous system (CNS)
experimental autoimmune encephalomyelitis (EAE)
mouse
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02337/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02337/full

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