Utilization of AlphaFold2 to Predict MFS Protein Conformations after Selective Mutation

Utilization of AlphaFold2 to Predict MFS Protein Conformations after Selective Mutation

The major facilitator superfamily (MFS) is the largest secondary transporter family and is responsible for transporting a broad range of substrates across the biomembrane. These proteins are involved in a series of conformational changes during substrate transport. To decipher the transport mechanis...

Full description

Bibliographic Details
Main Authors: Qingjie Xiao, Mengxue Xu, Weiwei Wang, Tingting Wu, Weizhe Zhang, Wenming Qin, Bo Sun
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
MFS transporter
selective mutation
predicted structure
multiple conformations
high accuracy
Online Access:https://www.mdpi.com/1422-0067/23/13/7235

Internet

https://www.mdpi.com/1422-0067/23/13/7235

Similar Items