Augmenting Insufficiently Accruing Oncology Clinical Trials Using Generative Models: Validation Study

Augmenting Insufficiently Accruing Oncology Clinical Trials Using Generative Models: Validation Study

BackgroundInsufficient patient accrual is a major challenge in clinical trials and can result in underpowered studies, as well as exposing study participants to toxicity and additional costs, with limited scientific benefit. Real-world data can provide external controls, but...

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Bibliographic Details
Main Authors: Samer El Kababji, Nicholas Mitsakakis, Elizabeth Jonker, Ana-Alicia Beltran-Bless, Gregory Pond, Lisa Vandermeer, Dhenuka Radhakrishnan, Lucy Mosquera, Alexander Paterson, Lois Shepherd, Bingshu Chen, William Barlow, Julie Gralow, Marie-France Savard, Christian Fesl, Dominik Hlauschek, Marija Balic, Gabriel Rinnerthaler, Richard Greil, Michael Gnant, Mark Clemons, Khaled El Emam
Format: Article
Language:English
Published: JMIR Publications 2025-03-01
Series:Journal of Medical Internet Research
Online Access:https://www.jmir.org/2025/1/e66821

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https://www.jmir.org/2025/1/e66821

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