Unilateral nephrectomy diminishes ischemic acute kidney injury through enhanced perfusion and reduced pro-inflammatory and pro-fibrotic responses.

Unilateral nephrectomy diminishes ischemic acute kidney injury through enhanced perfusion and reduced pro-inflammatory and pro-fibrotic responses.

While unilateral nephrectomy (UNx) is suggested to protect against ischemia-reperfusion injury (IRI) in the remaining kidney, the mechanisms underlying this protection remain to be elucidated. In this study, functional MRI was employed in a renal IRI rat model to reveal global and regional changes i...

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Bibliographic Details
Main Authors: Casper Kierulf-Lassen, Per Mose Nielsen, Haiyun Qi, Mads Damgaard, Christoffer Laustsen, Michael Pedersen, Søren Krag, Henrik Birn, Rikke Nørregaard, Bente Jespersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739457?pdf=render

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http://europepmc.org/articles/PMC5739457?pdf=render

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