Intracellular Environment Improvement of <i>Mycobacterium neoaurum</i> for Enhancing Androst-1,4-Diene-3,17-Dione Production by Manipulating NADH and Reactive Oxygen Species Levels

As one of the most significant steroid hormone precursors, androst-1,4-diene-3,17-dione (ADD) could be used to synthesize many valuable hormone drugs. The microbial transformation of sterols to ADD has received extensive attention in recent years. In a previous study, <i>Mycobacterium neoaurum...

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Bibliographic Details
Main Authors: Minglong Shao, Youxi Zhao, Yu Liu, Taowei Yang, Meijuan Xu, Xian Zhang, Zhiming Rao
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/21/3841