Design, Characterization, and Immune Augmentation of Docosahexaenoic Acid Nanovesicles as a Potential Delivery System for Recombinant HBsAg Protein

Design, Characterization, and Immune Augmentation of Docosahexaenoic Acid Nanovesicles as a Potential Delivery System for Recombinant HBsAg Protein

Recombinant HBsAg-loaded docosahexaenoic acid nanovesicles were successfully developed, lyophilized (LRPDNV) and characterized for their physico-chemical properties. The zetapotential (ZP) of LRPDNV was −60.4 ± 10.4 mV, and its polydispersity (PDI) was 0.201, with a % PDI of 74.8. The particle sizes...

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Bibliographic Details
Main Authors: Mohammed Ali Bakkari, Sivakumar S. Moni, Abdulrahman Alshammari, Ahmad Salawi, Muhammad H. Sultan, Osama A. Madkhali, Saad S. Alqahtani, Mohammad Firoz Alam, Emad Sayed Shaheen, Mohamed Eltaib Elmobark
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Vaccines
Subjects:
vaccine adjuvants
recombinant proteins
HBsAg
nanovesicles
docosahexaenoic acid
Online Access:https://www.mdpi.com/2076-393X/10/6/954

Internet

https://www.mdpi.com/2076-393X/10/6/954

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