Identification of Biologically Active Ganoderma lucidum Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer Activities in vitro

Identification of Biologically Active Ganoderma lucidum Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer Activities in vitro

We previously reported that Ganoderma lucidum extract (GLE) demonstrate significant anti-cancer activity against triple negative inflammatory breast cancer models. Herein, we aimed to elucidate the bioactive compounds of GLE responsible for this anti-cancer activity. We performed NMR, X-ray crystall...

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Bibliographic Details
Main Authors: Michelle M. Martínez-Montemayor, Taotao Ling, Ivette J. Suárez-Arroyo, Gabriela Ortiz-Soto, Camille L. Santiago-Negrón, Mercedes Y. Lacourt-Ventura, Anibal Valentín-Acevedo, Walter H. Lang, Fatima Rivas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Pharmacology
Subjects:
Ganoderma lucidum
ergosterol peroxide
breast cancer
EP derivatives
natural product
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00115/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00115/full

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