Time-Dependent and Organ-Specific Changes in Mitochondrial Function, Mitochondrial DNA Integrity, Oxidative Stress and Mononuclear Cell Infiltration in a Mouse Model of Burn Injury.

Time-Dependent and Organ-Specific Changes in Mitochondrial Function, Mitochondrial DNA Integrity, Oxidative Stress and Mononuclear Cell Infiltration in a Mouse Model of Burn Injury.

Severe thermal injury induces a pathophysiological response that affects most of the organs within the body; liver, heart, lung, skeletal muscle among others, with inflammation and hyper-metabolism as a hallmark of the post-burn damage. Oxidative stress has been implicated as a key component in deve...

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Bibliographic Details
Main Authors: Bartosz Szczesny, Attila Brunyánszki, Akbar Ahmad, Gabor Oláh, Craig Porter, Tracy Toliver-Kinsky, Labros Sidossis, David N Herndon, Csaba Szabo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4668069?pdf=render

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http://europepmc.org/articles/PMC4668069?pdf=render

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