Identification of copy neutral loss of heterozygosity on chromosomes 1p, 1q, and 6p among nonsyndromic cleft lip and/or without cleft palate with hypodontia

Identification of copy neutral loss of heterozygosity on chromosomes 1p, 1q, and 6p among nonsyndromic cleft lip and/or without cleft palate with hypodontia

Abstract Background Nonsyndromic cleft lip and/or without cleft palate (NSCL/P) with or without hypodontia is a common developmental aberration in humans and animals. This study aimed to identify the loss of heterozygosity (LOH) involved in hypodontia and NSCL/P pathogenesis. Methods This is a cross...

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Bibliographic Details
Main Authors: Norliana Ghazali, Normastura Abd Rahman, Thirumulu Ponnuraj Kannan, Azlina Ahmad, Sarina Sulong
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Oral Health
Subjects:
Cleft lip
Cleft palate
Tooth loss
Loss of heterozygosity
Oligonucleotide array sequence analysis
Microsatellite repeats
Online Access:https://doi.org/10.1186/s12903-023-03464-3

Internet

https://doi.org/10.1186/s12903-023-03464-3

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