Identification of copy neutral loss of heterozygosity on chromosomes 1p, 1q, and 6p among nonsyndromic cleft lip and/or without cleft palate with hypodontia

Abstract Background Nonsyndromic cleft lip and/or without cleft palate (NSCL/P) with or without hypodontia is a common developmental aberration in humans and animals. This study aimed to identify the loss of heterozygosity (LOH) involved in hypodontia and NSCL/P pathogenesis. Methods This is a cross...

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Main Authors: Norliana Ghazali, Normastura Abd Rahman, Thirumulu Ponnuraj Kannan, Azlina Ahmad, Sarina Sulong
格式: Article
語言:English
出版: BMC 2023-11-01
叢編:BMC Oral Health
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在線閱讀:https://doi.org/10.1186/s12903-023-03464-3