IgG antibodies mediated gold nanoparticles conjugated to methotrexate as targeted chemotherapy for lung cancer

AbstractVincamine, a natural chemical, was used as a reducing agent in the synthesis of IgG antibodies mediated biogenic gold nanoparticles (IgGAuNPs). Eventually, the synthesised IgGAuNPs were bioconjugated with the chemotherapeutic drug methotrexate (MTX-IgGAuNPs). The IgG isotype can target cance...

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Bibliographic Details
Main Authors: Asad Syed, Abu Baker, Mohamed Mohany, Abdallah M. Elgorban, Mohd Sajid Khan, Salim S. Al-Rejaie
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2023.2242419