Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth

Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth

Abstract Tumor-associated macrophages (TAMs) account for 30–50% of glioma microenvironment. The interaction between glioma tumor cells and TAMs can promote tumor progression, but the intrinsic mechanisms remain unclear. Herein, we reported that soluble LRIG3 (sLRIG3) derived from glioma tumor cells...

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Bibliographic Details
Main Authors: Youwei Li, Wei Wang, Xiaoshuang Hou, Wenda Huang, Po Zhang, Yue He, Baofeng Wang, Qiuhong Duan, Feng Mao, Dongsheng Guo
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05555-z

Internet

https://doi.org/10.1038/s41419-023-05555-z

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