Synthesis of the heterocyclic core of the D-series GE2270

Synthesis of the heterocyclic core of the D-series GE2270

A straightforward enantiomerically pure synthesis of the heterocyclic core of the D-series GE2270 is reported. The synthetic strategy combines the Hantzsch thiazole’s building condensation with a cross-coupling reaction including direct C–H hetarylation to build and connect step-by-step thiazolyl mo...

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Detalhes bibliográficos
Main Authors: Christophe Berini, Thibaut Martin, Pierrik Lassalas, Francis Marsais, Christine Baudequin, Christophe Hoarau
Formato: Artigo
Idioma:English
Publicado em: Beilstein-Institut 2017-07-01
Colecção:Beilstein Journal of Organic Chemistry
Assuntos:
antibiotic
bromination
BSC
C–H arylation
cross-coupling
Hantzsch synthesis
thiopeptide
Acesso em linha:https://doi.org/10.3762/bjoc.13.137

Internet

https://doi.org/10.3762/bjoc.13.137

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