CK2α/CSNK2A1 Induces Resistance to Doxorubicin through SIRT6-Mediated Activation of the DNA Damage Repair Pathway

CK2α/CSNK2A1 Induces Resistance to Doxorubicin through SIRT6-Mediated Activation of the DNA Damage Repair Pathway

CK2α/CSNK2A1 is involved in cancer progression by phosphorylating various signaling molecules. Considering the role of CSNK2A1 in cancer progression and the phosphorylation of SIRT6 and the role of SIRT6 in chemoresistance through the DNA damage repair pathway, CSNK2A1 and SIRT6 might be involved in...

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Bibliographic Details
Main Authors: Usama Khamis Hussein, Asmaa Gamal Ahmed, Yiping Song, Kyoung Min Kim, Young Jae Moon, Ae-Ri Ahn, Ho Sung Park, Su Jin Ahn, See-Hyoung Park, Jung Ryul Kim, Kyu Yun Jang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
osteosarcoma
CSNK2A1
SIRT6
doxorubicin
DNA damage
prognosis
Online Access:https://www.mdpi.com/2073-4409/10/7/1770

Internet

https://www.mdpi.com/2073-4409/10/7/1770

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