Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments

Attenuation of neuroinflammation reverses Adriamycin-induced cognitive impairments

Abstract Numerous clinical studies have established the debilitating neurocognitive side effects of chemotherapy in the treatment of breast cancer, often referred as chemobrain. We hypothesize that cognitive impairments are associated with elevated microglial inflammation in the brain. Thus, either...

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Bibliographic Details
Main Authors: Barrett D. Allen, Lauren A. Apodaca, Amber R. Syage, Mineh Markarian, Al Anoud D. Baddour, Harutyun Minasyan, Leila Alikhani, Celine Lu, Brian L. West, Erich Giedzinski, Janet E. Baulch, Munjal M. Acharya
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Acta Neuropathologica Communications
Subjects:
Chemotherapy
Adriamycin
Doxorubicin
Chemobrain
Neuroinflammation
Cognitive dysfunction
Online Access:http://link.springer.com/article/10.1186/s40478-019-0838-8

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http://link.springer.com/article/10.1186/s40478-019-0838-8

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