The Effects of Various Food Products on Bisphosphonate’s Availability

The bioavailability of orally administered bisphosphonates is very low (<1%) due to their short absorption window in the proximal duodenum and high affinity for food. Food ingredients are able to bind the drug, but the presence of food extends the residence time of bisphosphonates in the absorpti...

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Bibliographic Details
Main Authors: Monika Zielińska, Grzegorz Garbacz, Jaroslaw Sczodrok, Adam Voelkel
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/4/717