Design of a Randomized Placebo-Controlled Trial to Evaluate the Anti-inflammatory and Senolytic Effects of Quercetin in Patients Undergoing Coronary Artery Bypass Graft Surgery

Design of a Randomized Placebo-Controlled Trial to Evaluate the Anti-inflammatory and Senolytic Effects of Quercetin in Patients Undergoing Coronary Artery Bypass Graft Surgery

Background: Following an acute coronary syndrome, patients display an elevated inflammatory profile, promoted in part by cellular senescence. For patients requiring a coronary artery bypass (CABG) surgery, exposure to the surgical intervention and cardiopulmonary bypass further exacerbate their resi...

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Bibliographic Details
Main Authors: Olina Dagher, Pauline Mury, Pierre-Emmanuel Noly, Annik Fortier, Guillaume Lettre, Eric Thorin, Michel Carrier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
coronary artery bypass grafting
quercetin
inflammation
senescence
senolytic
angiopoietin-like 2
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.741542/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.741542/full

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