Duplicated antibiotic resistance genes reveal ongoing selection and horizontal gene transfer in bacteria

Abstract Horizontal gene transfer (HGT) and gene duplication are often considered as separate mechanisms driving the evolution of new functions. However, the mobile genetic elements (MGEs) implicated in HGT can copy themselves, so positive selection on MGEs could drive gene duplications. Here, we us...

Full description

Bibliographic Details
Main Authors: Rohan Maddamsetti, Yi Yao, Teng Wang, Junheng Gao, Vincent T. Huang, Grayson S. Hamrick, Hye-In Son, Lingchong You
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45638-9