L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin

L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin

<p>Abstract</p> <p>Background</p> <p>Autotaxin (ATX, NPP-2), originally purified as a potent tumor cell motility factor, is now known to be the long-sought plasma lysophospholipase D (LPLD). The integrity of the enzymatic active site, including three crucial histidine m...

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Bibliographic Details
Main Authors: Schiffmann Elliott, Liotta Lance A, Bandle Russell W, Ptaszynska Malgorzata, Koh Eunjin, Clair Timothy, Stracke Mary L
Format: Article
Language:English
Published: BMC 2005-02-01
Series:Lipids in Health and Disease
Online Access:http://www.lipidworld.com/content/4/1/5

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http://www.lipidworld.com/content/4/1/5

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