L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin
<p>Abstract</p> <p>Background</p> <p>Autotaxin (ATX, NPP-2), originally purified as a potent tumor cell motility factor, is now known to be the long-sought plasma lysophospholipase D (LPLD). The integrity of the enzymatic active site, including three crucial histidine m...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2005-02-01
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Series: | Lipids in Health and Disease |
Online Access: | http://www.lipidworld.com/content/4/1/5 |