In Vivo Evaluation of DMSA-Coated Magnetic Nanoparticle Toxicity and Biodistribution in Rats: A Long-Term Follow-Up

In Vivo Evaluation of DMSA-Coated Magnetic Nanoparticle Toxicity and Biodistribution in Rats: A Long-Term Follow-Up

This work presents a long-term follow-up (300 days) of rats after a single intravenous injection of DMSA-coated magnetite nanoparticles (DMSA-MNP). The animals were systematically evaluated by hematological, biochemical, and ultrasound examinations, monitoring the same animal over time. In addition,...

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Bibliographic Details
Main Authors: Fernanda Paulini, Aline R. M. Marangon, Carolina L. Azevedo, Juliana L. M. Brito, Marcelle S. Lemos, Marcelo H. Sousa, Fabiane H. Veiga-Souza, Paulo E. N. Souza, Carolina M. Lucci, Ricardo B. Azevedo
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Nanomaterials
Subjects:
nanotechnology
nanotoxicology
nanosafety
iron nanoparticles
IONPs
dimercaptosuccinic acid
Online Access:https://www.mdpi.com/2079-4991/12/19/3513

Internet

https://www.mdpi.com/2079-4991/12/19/3513

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