Human endothelial cells and fibroblasts express and produce the coagulation proteins necessary for thrombin generation

Abstract In a previous study, we reported that human endothelial cells (ECs) express and produce their own coagulation factors (F) that can activate cell surface FX without the additions of external proteins or phospholipids. We now describe experiments that detail the expression and production in E...

Full description

Bibliographic Details
Main Authors: Clay T. Cohen, Nancy A. Turner, Joel L. Moake
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01360-w