Cyano- and Ketone-Containing Selenoesters as Multi-Target Compounds against Resistant Cancers

Cyano- and Ketone-Containing Selenoesters as Multi-Target Compounds against Resistant Cancers

Fifteen selenocompounds, comprising of eight ketone-containing selenoesters (<b>K1</b>–<b>K8</b>, also known as oxoselenoesters) and seven cyano-containing selenoesters (<b>N1</b>–<b>N7</b>, known also as cyanoselenoesters), have been designed, synthes...

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Bibliographic Details
Main Authors: Nikoletta Szemerédi, Simona Dobiasová, Noemi Salardón-Jiménez, Annamária Kincses, Márta Nové, Giyaullah Habibullah, Clotilde Sevilla-Hernández, Miguel Benito-Lama, Francisco-Javier Alonso-Martínez, Jitka Viktorová, Gabriella Spengler, Enrique Domínguez-Álvarez
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
multidrug resistance
efflux pump
ABCB1
apoptosis
selenium
cancer
Online Access:https://www.mdpi.com/2072-6694/13/18/4563

Internet

https://www.mdpi.com/2072-6694/13/18/4563

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