Effects of rheumatoid arthritis associated transcriptional changes on osteoclast differentiation network in the synovium

Background Osteoclast differentiation in the inflamed synovium of rheumatoid arthritis (RA) affected joints leads to the formation of bone lesions. Reconstruction and analysis of protein interaction networks underlying specific disease phenotypes are essential for designing therapeutic interventions...

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Bibliographic Details
Main Authors: Shilpa Harshan, Poulami Dey, Srivatsan Ragunathan
Format: Article
Language:English
Published: PeerJ Inc. 2018-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/5743.pdf