Design, Synthesis and Cytotoxicity Study of Primary Amides as Histone Deacetylase Inhibitors
Primary amide derivatives as histone deacetylase inhibitors (HDACIs) are very rare. This paper describes the synthesis of primary amide derivatives (compounds 6 and 7) that have the requirements to be histone deacetylase inhibitors of the zinc-binding type. Both of them exhibited good cytotoxicity a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Pharmacy University of Baghdad
2019-12-01
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| Series: | Iraqi Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/933 |