Circulating HFMD-associated coxsackievirus A16 is genetically and phenotypically distinct from the prototype CV-A16.

Human enteroviruses (HEV) have been linked to hand, foot, and mouth disease (HFMD) in the Pacific and Southeast Asia for decades. Many cases of HFMD have been attributed to coxsackievirus A16 (CV-A16, CA16), based on only partial viral genome determination. Viral phenotypes are also poorly defined....

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Main Authors: Wei Wei, Haoran Guo, Jingliang Li, Sangsang Ren, Zhenhong Wei, Wanguo Bao, Xiaoming Hu, Ke Zhao, Wenyan Zhang, Yulai Zhou, Fei Sun, Richard Markham, Xiao-Fang Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3988102?pdf=render