Improvement of a 1D Population Balance Model for Twin-Screw Wet Granulation by Using Identifiability Analysis

Improvement of a 1D Population Balance Model for Twin-Screw Wet Granulation by Using Identifiability Analysis

Recently, the pharmaceutical industry has undergone changes in the production of solid oral dosages from traditional inefficient and expensive batch production to continuous manufacturing. The latest advancements include increased use of continuous twin-screw wet granulation and application of advan...

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Bibliographic Details
Main Authors: Ana Alejandra Barrera Jiménez, Daan Van Hauwermeiren, Michiel Peeters, Thomas De Beer, Ingmar Nopens
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
granulation
wet granulation
granules
continuous manufacturing
PAT
population balance modeling
Online Access:https://www.mdpi.com/1999-4923/13/5/692

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https://www.mdpi.com/1999-4923/13/5/692

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