Novel fatty acyl substrates for myristoyl-CoA:protein N-myristoyl-transferase.

Myristoyl-CoA:protein N-myristoyltransferase (NMT) catalyzes the covalent attachment of myristic acid to the NH2-terminal Gly residues of a number of viral and cellular proteins. The remarkable specificity of this enzyme for myristoyl CoA observed in vivo appears to arise in large part from a cooper...

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Bibliographic Details
Main Authors: RO Heuckeroth, E Jackson-Machelski, SP Adams, NS Kishore, M Huhn, A Katoh, T Lu, GW Gokel, JI Gordon
Format: Article
Language:English
Published: Elsevier 1990-06-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752042752X