Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation.

Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation.

During inflammation polymorphonuclear neutrophils (PMNs) traverse venular walls, composed of the endothelium, pericyte sheath and vascular basement membrane. Compared to PMN transendothelial migration, little is known about how PMNs penetrate the latter barriers. Using mouse models and intravital mi...

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Bibliographic Details
Main Authors: Shijun Wang, Canhong Cao, Zhongming Chen, Vytas Bankaitis, Eleni Tzima, Nader Sheibani, Keith Burridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448630?pdf=render

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http://europepmc.org/articles/PMC3448630?pdf=render

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