LATS2 degradation promoted fibrosis damage and rescued by vitamin K3 in lupus nephritis
Abstract Background Lupus nephritis (LN) is the most common complication of systemic lupus erythematosus (SLE). The limited treatment options for LN increase the economic burdens on patients. Because fibrotic progression leads to irreversible renal damage in LN patients and further progresses to chr...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | Arthritis Research & Therapy |
Online Access: | https://doi.org/10.1186/s13075-024-03292-y |