LATS2 degradation promoted fibrosis damage and rescued by vitamin K3 in lupus nephritis

LATS2 degradation promoted fibrosis damage and rescued by vitamin K3 in lupus nephritis

Abstract Background Lupus nephritis (LN) is the most common complication of systemic lupus erythematosus (SLE). The limited treatment options for LN increase the economic burdens on patients. Because fibrotic progression leads to irreversible renal damage in LN patients and further progresses to chr...

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Bibliographic Details
Main Authors: Chen Cheng, Hao Yang, Chan Yang, Juan Xie, Jinshen Wang, Luping Cheng, Jianfu He, Honglian Li, Haoxing Yuan, Fangfang Guo, Minmin Li, Shuwen Liu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Arthritis Research & Therapy
Online Access:https://doi.org/10.1186/s13075-024-03292-y

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