393 Harnessing the potential of transcriptional adaptation as a mechanism for rare Amyotrophic lateral sclerosis
OBJECTIVES/GOALS: Transcriptional adaptation is a phenomenon in which a mutation in one gene leads to the genetic compensation of another homogenous gene. Understanding the mechanism of transcriptional adaptation may contribute to an explanation for variation in clinical manifestations of rare Amyot...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2024-04-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866124003431/type/journal_article |