Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model

Aims: Glucose-insulin-potassium (GIK) is protective following cardiac myocyte ischaemia-reperfusion (IR) injury, however the role of GIK in protecting skeletal muscle from IR injury has not been evaluated. Given the similar mechanisms by which cardiac and skeletal muscle sustain an IR injury, we hy...

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Bibliographic Details
Main Authors: Daniel B. Buchalter, David J. Kirby, Utkarsh Anil, Sanjit R. Konda, Philipp Leucht
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2023-03-01
Series:Bone & Joint Research
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.123.BJR-2022-0312.R1