Hemokinin-1 Gene Expression Is Upregulated in Trigeminal Ganglia in an Inflammatory Orofacial Pain Model: Potential Role in Peripheral Sensitization

Hemokinin-1 Gene Expression Is Upregulated in Trigeminal Ganglia in an Inflammatory Orofacial Pain Model: Potential Role in Peripheral Sensitization

A large percentage of primary sensory neurons in the trigeminal ganglia (TG) contain neuropeptides such as tachykinins or calcitonin gene-related peptide. Neuropeptides released from the central terminals of primary afferents sensitize the secondary nociceptive neurons in the trigeminal nucleus caud...

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Bibliographic Details
Main Authors: Timea Aczél, Angéla Kecskés, József Kun, Kálmán Szenthe, Ferenc Bánáti, Susan Szathmary, Róbert Herczeg, Péter Urbán, Attila Gyenesei, Balázs Gaszner, Zsuzsanna Helyes, Kata Bölcskei
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
orofacial pain
hemokinin-1
trigeminal ganglia
complete Freund’s adjuvant
macrophages
satellite glial cells
Online Access:https://www.mdpi.com/1422-0067/21/8/2938

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https://www.mdpi.com/1422-0067/21/8/2938

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