Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model

Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model

Tumor-necrosis-factor-associated apoptosis-inducing ligand (TRAIL) is one of the most promising therapeutic cytokines that selectively induce apoptosis in tumor cells. It is known that membrane vesicles (MVs) can carry the surface markers of parental cells. Therefore, MVs are of interest as a tool f...

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Bibliographic Details
Main Authors: Daria S. Chulpanova, Tamara V. Pukhalskaia, Zarema E. Gilazieva, Yuliya V. Filina, Milana N. Mansurova, Albert A. Rizvanov, Valeriya V. Solovyeva
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Current Issues in Molecular Biology
Subjects:
tumor necrosis factor-related apoptosis-inducing ligand
mesenchymal stem cells
extracellular vesicles
cytochalasin B
extrinsic apoptosis pathway
cancer therapy
Online Access:https://www.mdpi.com/1467-3045/45/1/38

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https://www.mdpi.com/1467-3045/45/1/38

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