Development and Validation of a Non-invasive Model to Predict Liver Histological Lesions in Chronic Hepatitis B Patients With Persistently Normal Alanine Aminotransferase and Detectable Viremia

Development and Validation of a Non-invasive Model to Predict Liver Histological Lesions in Chronic Hepatitis B Patients With Persistently Normal Alanine Aminotransferase and Detectable Viremia

BackgroundA critical and controversial issue is whether antiviral therapy should be recommended in chronic hepatitis B virus (HBV) infection patients with persistently normal alanine aminotransferase (PNALT) and detectable HBV DNA. The study aimed to develop a non-invasive model for predicting signi...

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Bibliographic Details
Main Authors: Qiankun Hu, Qianqian Wang, Wei Xu, Chenlu Huang, Shuai Tao, Xun Qi, Yi Zhang, Xinyan Li, Xuhua Jiang, Jie Song, Qiang Li, Liang Chen, Yuxian Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
chronic hepatitis B
significant liver histological changes
persistently normal alanine aminotransferase
non-invasive model
antiviral therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.944547/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.944547/full

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