Gene Amplification in Tumor Cells: Developed De Novo or Adopted from Stem Cells

Gene amplifications have been known for several decades as physiological processes in amphibian and flies, e.g., during eggshell development in <i>Drosophila</i> and as part of pathological processes in humans, specifically in tumors and drug-resistant cells. The long-held belief that a...

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Bibliographic Details
Main Authors: Ulrike Fischer, Eckart Meese
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/1/148