Right Ventricle Remodeling Metabolic Signature in Experimental Pulmonary Hypertension Models of Chronic Hypoxia and Monocrotaline Exposure

Right Ventricle Remodeling Metabolic Signature in Experimental Pulmonary Hypertension Models of Chronic Hypoxia and Monocrotaline Exposure

Introduction: Over time and despite optimal medical management of patients with pulmonary hypertension (PH), the right ventricle (RV) function deteriorates from an adaptive to maladaptive phenotype, leading to RV failure (RVF). Although RV function is well recognized as a prognostic factor of PH, no...

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Bibliographic Details
Main Authors: Thaïs Hautbergue, Fabrice Antigny, Angèle Boët, François Haddad, Bastien Masson, Mélanie Lambert, Amélie Delaporte, Jean-Baptiste Menager, Laurent Savale, Jérôme Le Pavec, Elie Fadel, Marc Humbert, Christophe Junot, François Fenaille, Benoit Colsch, Olaf Mercier
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
RV dysfunction
MCT
chronic-hypoxia
arginine
tryptophan
purine
Online Access:https://www.mdpi.com/2073-4409/10/6/1559

Internet

https://www.mdpi.com/2073-4409/10/6/1559

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