Coordinated expansion of memory T follicular helper and B cells mediates spontaneous clearance of HCV reinfection

Coordinated expansion of memory T follicular helper and B cells mediates spontaneous clearance of HCV reinfection

IntroductionFollicular helper T cells are essential for helping in the maturation of B cells and the production of neutralizing antibodies (NAbs) during primary viral infections. However, their role during recall responses is unclear. Here, we used hepatitis C virus (HCV) reinfection in humans as a...

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Bibliographic Details
Main Authors: Mohamed Eisa, Elsa Gomez-Escobar, Nathalie Bédard, Nourtan F. Abdeltawab, Nicol Flores, Sabrina Mazouz, Alizée Fieffé-Bédard, Patrick Sakayan, John Gridley, Mohamed S. Abdel-Hakeem, Julie Bruneau, Arash Grakoui, Naglaa H. Shoukry
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Immunology
Subjects:
hepatitis C virus
B cells
neutralizing antibodies
Tfh and immunity
reinfection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1403769/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1403769/full

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