Recent Advances in the Clinical Targeting of Hedgehog/GLI Signaling in Cancer

The Hedgehog/GLI signaling pathway plays an important role in normal embryonic tissue development and has been implicated in the pathogenesis of various human cancers. In this review article, we summarize pre-clinical evidence supporting the suitability of targeting this signaling pathway in cancers...

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Bibliographic Details
Main Authors: Hao Xie, Brooke D. Paradise, Wen Wee Ma, Martin E. Fernandez-Zapico
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/5/394